ADDTabz Plus™ and CDP-Choline
Choline CDP is a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources.
Stabilized CDP-Choline (cytidine 5’diphosphocholine) is an essential intermediate for the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue (30%). CDP-choline is metabolized to yield the free nucleotides cytidine and choline. Scientific research demonstrates that CDP-Choline consumption promotes brain metabolism by enhancing the synthesis of the neurotransmitter acetylcholine, restoring phospholipid content in the brain and regulation of neuronal membrane excitability and osmolarity (by its effect on the ATP-dependent sodium and potassium pumps. CDP-Choline has the very unique property of being able to penetrate the blood-brain barrier.
Brain cells use choline to support the integrity of the cell membrane, protect against neurotoxins, synthesize neurotransmitters and support brain cell metabolic function. Brain cells produce very small amounts of choline, thereby necessitating dietary sources. Phosphatidylcholine is the major structural and functional component of brain cell membranes. Without phosphatidylcholine, brain cells lose their youthful function and suffer the degenerative structural changes associated with aging. CDP-choline is an essential intermediate in the conversion of choline to phosphatidylcholine and may be a key missing